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Announcements

Congratulations Dr. Sebastiampillai!

Join us in congratulating Stephanie for passing her defence! Wishing you all the best as you write your future!

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Congratulations Dr. Potter!

Join us in congratulating Nicole for passing her defence! We're so proud of all the work you've knitted together in the past 6 years!

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Congratulations Dr. Bu!

 Join us in congratulating Jamie for passing her defence! Jamie, we love you ❤️ (and sugars... and crosswords and pokemon...)

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Congratulations Jamie for publishing in the Journal of the American Chemical Society!

We have developed a new bioorthogonal reaction usingTePhe, a tellurophene-based phenylalanine analogue. This reaction, called oxidation-controlled, strain-promoted tellurophene-alkyne cycloaddition (OSTAC), involves mild oxidation of tellurophene to create a reactive species that rapidly cyclizes with bicyclo[6.1.0]nonyne (BCN). OSTAC allows for selective labeling of proteins in complex mixtures and can be combined with other reactions like SPAAC and CuAAC, showing broad potential in... view

Let's wear our PPE 🥽

Pokemon reminded us to wear our personal protective equipment. Prioritize safety, unlock better chemistry!

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Congratulations Amanda!

A round of applause for Master Amanda who completed her M.Sc. exit seminar on desulfurative cross-coupling of thioglycosides! Your hard work has set a high bar for excellence in our lab. Well done!*pictured is Amanda's pet snake Ruby 🐍

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Congratulations to Alex on publishing in ACS Chemical Biology!

Our new paper presents how N-azidoacetylglucosamine (GlcNAz) can be incorporated into bacterial peptidoglycan for metabolic labeling in Escherichia coli. By the expression of NahK in E. coli, the cytosolic production of UDP-GlcNAz and preferential incorporation into peptidoglycan (PGN) over other sites like poly-β-1,6-N-acetylglucosamine (PNAG), lipopolysaccharide (LPS), or enterobacterial common antigen (ECA) was revealed, providing insights for future development of carbohydrate-based... view

Cheers to Nicole on publishing in ACS Bioconjugate Chemistry!

See our recent publication (starred with Editor's Choice⭐) on designing and implementing the first mass cytometry ligands compatible with the HaloTag system. Employing "click"-amenable HaloTag warheads conjugated metal-chelating polymers, we demonstrated successful labelling of HEK293T cells. https://doi.org/10.1021/acs.bioconjchem.3c00434 

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Congratulations Daniel and Hunter for getting your work accepted to ACS Bioconjugate Chemistry!

Our newest publication offers a promising addition to the toolbox of bioorthogonal reactions in chemical biology! We present a cascade reaction between N-allylglyoxylamide and N-alkylhydroxylamine, catalyzed by 5-methoxyanthranilic acid, combining the reactivity of nitrones with the simplicity of aldehydes, demonstrating bioorthogonality in complex cell lysates and on the surface of HEK293 cells. https://doi.org/10.1021/acs.... view

🌲O Coatmas Tree🌲

As the holidays approach, the Nitz group is donning up with festivity ❄️ We present to you... The Coatmas Tree! Transforming perished lab coats into a festive decoration, we are embracing the holiday cheer with a dash of science and sustainability.

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