@article {292,
	title = {Quantifying the Effect of Dietary Microplastics on the Potential for Biological Uptake of Environmental Contaminants and Polymer Additives.},
	journal = {Environ Sci Technol},
	year = {2025},
	month = {2025 Apr 22},
	abstract = {<p>The pervasive presence of microplastic in food raises the question of how this presence influences the uptake of organic contaminants from the gastrointestinal tract. Depending on the relative contamination of diet and microplastics, the latter can act either as a vector of contaminants facilitating biological uptake or as a contaminant sink whose sorptive capacity does not diminish during digestion. A comprehensive understanding of these effects ultimately requires the quantification of the effect of microplastics on the thermodynamic driving force responsible for diffusion from the gut lumen to the tissues of an organism. Using silicone-based equilibrium sampling, we quantified the effect of polyvinyl chloride (PVC) microplastics on the fugacity of polychlorinated biphenyls (PCBs) and two polymer additives in dietary and fecal samples of a zoo-housed polar bear. Although PVC microplastics at concentrations well above current observations reduced the fugacities of spiked isotopically labeled PCBs in the polar bear diet and feces slightly, but significantly, leaching from these microplastics greatly elevated fugacities of the additives UV-328 and octabenzone in these samples. The impact of microplastics in the diet on the biological uptake of environmental hydrophobic organic contaminants is likely to be negligible. Microplastics have the potential to be effective vectors for the dietary uptake of polymer additives.</p>},
	issn = {1520-5851},
	doi = {10.1021/acs.est.5c02616},
	author = {Ng, Desmond and Chen, Yuhao and Lei, Ying Duan and Chen, Wanzhen and Peng, Hui and Gourlie, Sarra and Wania, Frank}
}
@article {295,
	title = {Semiquantitative Nontargeted Screening of Organophosphorus Plastic Additives in Consumer Products Using P NMR.},
	journal = {Environ Sci Technol},
	year = {2025},
	month = {2025 Jun 02},
	abstract = {<p>Mass spectrometry (MS) is typically employed for the nontargeted identification of unknown organophosphorus compounds (OPCs). However, quantitative analysis remains a major challenge due to the lack of authentic standards for most of the OPCs. A phosphorus NMR (P NMR) method for semiquantitative nontargeted analysis was developed and applied to 37 different plastic products, where OPCs were detected in nine at high concentrations (86.9-7206 nmol/g). Three classes of compounds were detected with clearly separated chemical shifts, including organophosphites (δ = 125-140 ppm) and organophosphates (δ = (-20)-5 ppm), as well as an unexpected "unannotated" class (δ = 5-20 ppm). The "unannotated" class was subsequently identified as organophosphite diesters and confirmed through in-lab hydrolysis trials. In this work, we demonstrate how a P NMR method may serve as a powerful analytical tool when combined with mass spectrometry for the nontargeted analysis of OPCs. We highlight organophosphite diesters as a novel class of compounds which represent a potential source of organophosphate diesters in the environment.</p>},
	issn = {1520-5851},
	doi = {10.1021/acs.est.5c02789},
	author = {Chen, Wanzhen and Miller, Jolie M and Burns, Darcy C and Almuhtaram, Husein and Andrews, Robert C and Peng, Hui}
}
@article {217,
	title = {Defining the Chemical Additives Driving In Vitro Toxicities of Plastics},
	journal = {Environ. Sci. Technol.},
	year = {2022},
	author = {Chen, Wanzhen and Gong, Yufeng and Michael, McKie and Husein, Almuhtaram and Sun, Jianxian and Barrett, Holly and Yang, Diwen and Wu, Menghong and Andrews, Robert and Peng, Hui}
}
