Title | Borinic acid-catalyzed stereo- and site-selective synthesis of beta-glycosylceramides |
Publication Type | Journal Article |
Year of Publication | 2017 |
Authors | D'Angelo, KA, Taylor, MS |
Journal | Chemical Communications |
Volume | 53 |
Issue | 44 |
Pagination | 5978 - 5980 |
Date Published | 2017 |
ISBN Number | 1359-7345 |
Abstract | A method for activation of unprotected ceramides towards stereo- and site-selective glycosylation is described. Two-point binding of a diarylborinic acid catalyst to the ceramide accelerates its reactions with 'armed' glycosyl methanesulfonate donors, resulting in the formation of a [small beta]-glycosidic linkage at the primary OH group. |
URL | http://dx.doi.org/10.1039/C7CC01673E |
Short Title | Chem. Commun. |