
@article {109,
	title = {Carbon{\textendash}carbon bond-forming reactions of α-carbonyl carbocations: exploration of a reversed-polarity equivalent of enolate chemistry},
	journal = {Tetrahedron},
	volume = {67},
	year = {2011},
	month = {2011/9/30/},
	pages = {7586 - 7592},
	abstract = {<p>Carbon{\textendash}carbon bond-forming reactions of putative α-carbonyl carbocation intermediates generated by Lewis acid- or silver-promoted ionizations of toluenesulfonate or halide leaving groups are described. This under-exploited mode of reactivity represents an {\textquoteleft}umpolung{\textquoteright} of conventional enolate chemistry, and enables C{\textendash}C bond construction in both intra- and intermolecular contexts. Attempts to develop diastereoselective variants of this process using chiral ester and oxazolidinone-based auxiliaries are discussed.</p>},
	keywords = {Allylation, Carbocations, Friedel{\textendash}Crafts reaction, Lactams, Umpolung reactivity},
	isbn = {0040-4020},
	url = {http://www.sciencedirect.com/science/article/pii/S0040402011011148},
	author = {Lai, Ping-Shan and Dubland, Joshua A. and Sarwar, Mohammed G. and Chudzinski, Michael G. and Taylor, Mark S.}
}
